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At 24 hours the plasma levels of sildenafil had been even now about 200 ng/mL, in comparison with somewhere around 5 ng/mL when sildenafil was dosed alone. This can be according to ritonavir's marked outcomes over a broad array of P450 substrates. VIAGRA had no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTION